Specimen bank

Specimen bank

FIND manages collections of well-characterized disease samples (specimens), to support commercial and academic researchers in the development or evaluation of new and existing tools to improve diagnosis of infectious diseases in low- and middle-income countries.

Specimens are ethically collected in clinical trials, and made available for use by diagnostic developers.

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Specimen requests

Developers are invited to request specimens for use in diagnostic research. Each request is evaluated by the FIND Specimen Bank Review Committee (SBRC). The SBRC approves specimen requests based on:

  • Relevance to public health
  • Applicability of the technology in high-burden countries
  • Affordability of final product
  • Previous data or scientific evidence supporting the request

Following SBRC approval, samples are shipped worldwide.

Requesters are asked to cover handling fees and shipping costs. As FIND is a non-profit organization, handling fees provide ongoing support for Specimen Bank activities, including rental of freezers, software maintenance and personnel costs.

All FIND Specimen Bank recipients are asked to report back on data derived from specimen use, and are strongly encouraged to share results with the scientific community.

Specimen collection

Specimens are collected at qualified clinics, under a protocol approved by an ethical review board and with informed consent from patients meeting the inclusion criteria for specimen collection. FIND follows good clinical and laboratory practices in obtaining and processing specimens, which are collected specifically for product development purposes, or as a complement to clinical trial activities.

The FIND Specimen Bank hosts over 400,000 specimens of whole blood, serum, plasma, urine, sputum, saliva, DNA (bacterial), PAXgene tubes and culture isolates.

Typical specimen characterizations may include microscopy, bacterial culture, molecular tests (e.g. PCR and Xpert® MTB/Rif), antigen detection tests and antibody detection tests (e.g. serological tests).

Details on the collections held for each disease area, including specimen types and characterization:

Fever  Hepatitis C  Malaria  Tuberculosis

FIND also hosts a TB collection for WHO/TDR, and contributes to the WHO specimen collections for human African trypanosomiasis and leishmaniasis.

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