Specimen types & characterization: fever

Sample type	Characterization*	Volume	Origin
Plasma EDTA	Bacterial infection (confirmed, probable) with/without malaria co-infection Non-bacterial infection (confirmed, probable) with/without malaria co-infection	0.2 mL	Africa
Plasma heparin		0.1 mL	Africa
Serum		0.2 mL	Africa
Urine		1 mL	Africa
Whole blood EDTA		0.5 mL	Africa
Whole blood PAXgene tubes		1 mL	Africa

*Two-step characterization process includes extensive laboratory testing:

Each study subject is classified by an electronic algorithm based on microbiological test results according to predefined criteria
A panel of three experts review all remaining study subjects based on patient history, clinical and microbiological data for each patient.