Specimen types & characterization: fever
The FIND fever biobank holds an extensively characterized specimen collection from acute febrile patients grouped by symptoms, including respiratory, gastrointestinal, and urinary tract infection. Sample requests to this specimen bank can be placed for specific symptomatic patients and/or characterization methods. Information about patients, symptom-based groups, sample characterization process, and tests performed can be found in this paper [PDF].
| Sample type | Characterization* | Volume | Origin |
| Plasma EDTA |
Bacterial infection with/without malaria co-infection Non-bacterial infection with/without malaria co-infection |
0.2 mL | Africa; Latin America |
| Plasma heparin | 0.1 mL | Africa | |
| Serum | 0.2 mL | Africa; Latin America | |
| Urine | 1 mL | Africa; Latin America | |
| Whole blood EDTA | 0.5 mL | Africa; Latin America | |
| Whole blood PAXgene tubes | 1 mL | Africa; Latin America |
*Two-step characterization process includes extensive laboratory testing:
- Each study subject is classified by an electronic algorithm based on microbiological test results according to predefined criteria
- A panel of three experts review all remaining study subjects based on patient history, clinical and microbiological data for each patient.
See QUICK LINKS for more information.
Quick links
- Laboratory investigation of fever (factsheet)
- Electronic classification of fever (factsheet)
- Bacterial vs non-bacterial classification process (factsheet)
- Bacterial versus non-bacterial infections: a methodology to support use-case-driven product development of diagnostics (Escafadal et al.)
- FIND project: Biomarkers for fever diagnostics (BFF-Dx)
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