WHO diagnostics guidance

This is a curated list of WHO guidance documents relevant to the areas in which we work.

Compendium of data and evidence-related tools for use in TB planning and programming
Technical Report on critical concentrations for drug susceptibility testing of isoniazid and the rifamycins (rifampicin, rifabutin and rifapentine)
SARS-CoV-2 antigen-detecting rapid diagnostic tests: an implementation guide
Lateral flow urine lipoarabinomannan assay (LF-LAM) for the diagnosis of active tuberculosis in people living with HIV
Evaluation of centralized assays for TB detection and detection of resistance to rifampicin and isoniazid
Recommended selection criteria for procurement of malaria rapid diagnostic tests
The use of next-generation sequencing technologies for the detection of mutations associated with drug resistance in Mycobacterium tuberculosis complex: technical guide
Best practices in child and adolescent tuberculosis care
Technical manual for drug susceptibility testing of medicines used in the treatment of tuberculosis
Methods manual for product testing of malaria rapid diagnostic tests
Guidelines on hepatitis B and C testing
Chest radiography in tuberculosis detection
The use of molecular line probe assays for the detection of resistance to second-line anti-tuberculosis drugs
Framework of indicators and targets for laboratory strengthening under the END TB Strategy
The use of molecular line probe assays for the detection of resistance to isoniazid and rifampicin
The use of loop-mediated isothermal amplification (TB-LAMP) for the diagnosis of pulmonary tuberculosis
Methods manual for laboratory quality control testing of malaria rapid diagnostic tests
Guidelines for the screening, care and treatment of persons with chronic hepatitis C infection
Procedures for product testing and lot testing. Information for RDT manufacturers and procurers (WHO-FIND Malaria RDT Evaluation Programme)
Methods manual: Microscopy for the detection, identification and quantification of malaria parasites on stained thick and thin blood films in research settings
Implementing tuberculosis diagnostics
Using the Xpert MTB/RIF assay to detect pulmonary and extrapulmonary tuberculosis and rifampicin resistance in adults and children
Xpert MTB/RIF assay for the diagnosis of pulmonary and extrapulmonary TB in adults and children
Good practices for selecting and procuring rapid diagnostic tests for malaria
Commercial serodiagnostic tests for diagnosis of tuberculosis
Automated real-time nucleic acid amplification technology for rapid and simultaneous detection of tuberculosis and rifampicin resistance: Xpert MTB/RIF system
Rapid implementation of the Xpert MTB/RIF diagnostic test
Noncommercial culture and drug-susceptibility testing methods for screening patients at risk for multidrug-resistance tuberculosis
Fluorescent light-emitting diode (LED) microscopy for diagnosis of tuberculosis
Same-day diagnosis of tuberculosis by microscopy
Guidance for development of national laboratory strategic plans