WHO catalogue of mutations in Mycobacterium tuberculosis and associated drug resistance. The what, when and how?

On 30 November 2021, from 14:00 to 17:00 CET, Timothy Rodwell, Senior Scientific Officer, is going to chair an online course on the WHO catalogue of mutations in Mycobacterium tuberculosis and associated drug resistance. Anita Suresh, Head of Sequencing, is going to speak on Understanding the role of Next Generation Sequencing for diagnosis of drug resistant TB.

WHO catalogue of mutations in Mycobacterium tuberculosis and associated drug resistance. The what, when and how?
The use of molecular tools for the diagnosis of tuberculosis (TB) and drug-resistant TB has had a significant impact on the management of TB globally. The use of more advanced technologies such as next-generation sequencing (NGS) is at the cusp of taking the current successes to the next level. However, a major hindrance has been the lack of a standardized single reference catalogue of mutations and their association with drug resistance. This is important for surveillance activities that already use such technologies, for manufacturers undertaking research and development and in preparation for the future programmatic use of these technologies.
Expected outputs/outcomes: Improved understanding of the use and special considerations when using NGS
Proficiency in using the WHO Catalogue of Mutations
Advanced knowledge on genotypic-phenotypic association studies
Session sponsor: Unitaid
Chair: Timothy Rodwell (University of California San Diego); Matteo Zignol (WHO)
Coordinators: Carl-Michael Nathanson (WHO); Nazir Ismail (WHO)
Target audience: Researchers, developers, laboratory experts, bioinformaticians, public health specialists, epidemiologists, programme managers
Speakers: Anita Suresh (FIND)
Nazir Ismail (WHO)
Timothy Walker (Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam)
Claudio Köser (Department of Genetics, University of Cambridge)
Paolo Miotto (Ospedale San Raffaele, Milan, Italy)

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