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Are we ready? State of preparedness of the 100 Days Mission

What is the 100 Days Mission?

In light of the COVID pandemic, the world came together and set a goal that, if (not when) another Public Health Emergency of International Concern (PHEIC) is declared, countries should be able to deploy diagnostics, vaccines and treatment within 100 days of the declaration. The International Pandemic Preparedness Secretariat was established to monitor global progress toward the 100 Days Mission.

4th IPPS Implementation report

On 31 January 2025, the IPPS launched its 4th Implementation Report, to which FIND was a substantial contributor. The conclusion: The world remains unprepared for another global pandemic, despite some national bright spots.

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Key Takeaways

  • Coordination in the R&D ecosystem continues to improve
  • Progress in R&D for diagnostics, therapeutics and vaccines has been uneven, with persistent access challenges
  • Expansion of geo-diversified trail networks and regional regulatory harmonization efforts support rapid response capabilities
    Ifedayo Adetifa

    Early diagnosis is critical for health security because it provides essential data required to inform the public health actions required to stop the spread of disease. The delayed progress towards equitable access to much needed diagnostics compromises our ability to respond to pandemic threats. FIND’s Pathogen Diagnostics Readiness Index shows only one of the top 20 high-risk pathogens has sufficient diagnostic tools available. Working in collaboration with partners like IPPS, FIND is committed to strengthening diagnostic surveillance and response systems to contain disease outbreaks thus improving pandemic preparedness.

    Ifedayo Adetifa

    Chief Transformation Officer/CEO

    Cape Town, launch of the IPPS report

    The report goes on to highlight the 3 key areas for action in 2025:

    1. Reinvigorate the therapeutics pipeline with a focus on early-stage R&D: Prioritise early-stage research and development to advance therapeutics for priority viral families, ensuring robust pipelines are prepared to address emerging threats.
    2. Enhance coordination to implement the Diagnostics 100DM roadmap: Collaborate with global partners to implement the 100 Days Mission diagnostics roadmap, improving alignment and advancing innovation across the diagnostics sector.
    3. Sustain clinical trial infrastructure and strengthen preparatory regulatory approaches: Ensure clinical trial networks remain functional between pandemics and adopt harmonised regulatory approaches to accelerate approvals during emergencies.

    Our Pandemic Threats programme

    We are building on advances catalysed by the COVID-19 pandemic to establish sustainable early-warning and response systems for known and emerging pathogens.

    Learn more